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  • Currently displaying 61 - 80 of 1091 publications
Unraveling the Structure and Dynamics of Ac-PHF6-NH<sub>2</sub> Tau Segment Oligomers.
I Stroganova, Z Toprakcioglu, H Willenberg, TPJ Knowles, AM Rijs
– ACS Chemical Neuroscience
(2024)
15,
3391
(doi: 10.1021/acschemneuro.4c00404)
Surface effects on functional amyloid formation.
AJ Dear, G Meisl, CG Taylor, UC Palmiero, SN Stubbe, Q Liu, P Arosio, S Linse, TPJ Knowles, M Andreasen
– Nanoscale
(2024)
16,
16172
(doi: 10.1039/d4nr01496k)
Aggregate-selective removal of pathological tau by clustering-activated degraders
J Benn, S Cheng, S Keeling, AE Smith, MJ Vaysburd, D Böken, LVC Miller, T Katsinelos, C Franco, E Dupré, C Danis, I Landrieu, L Buée, D Klenerman, LC James, WA McEwan
– Science
(2024)
385,
1009
(doi: 10.1126/science.adp5186)
SynPull: a novel method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
S Kedia, E Fertan, Y Wu, YP Zhang, G Meisl, JYL Lam, F Wiseman, WA McEwan, A Quaegebeur, MG Spillantini, JSH Danial, D Klenerman
(2024)
(doi: 10.1101/2024.08.24.609517)
Formation of Nano brillar Self-Healing Hydrogels using Antimicrobial Peptides
EG Wiita, Z Toprakcioglu, AK Jayaram, TPJ Knowles
– ACS Applied Materials and Interfaces
(2024)
16,
46167
(doi: 10.1021/acsami.4c11542)
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwӧger, TJ Krug, DA Weitz, M Lew, TPJ Knowles, RV Pappu
(2024)
(doi: 10.1101/2024.08.19.608662)
a-Synuclein oligomers form by secondary nucleation
CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles
– Nat Commun
(2024)
15,
7083
(doi: 10.1038/s41467-024-50692-4)
Competing addition processes give distinct growth regimes in the assembly of 1D filaments
SA Akram, T Brown, S Whitelam, G Meisl, TPJ Knowles, JD Schmit
(2024)
(doi: 10.48550/arxiv.2408.07257)
Dominance analysis to assess solute contributions to multicomponent phase equilibria.
D Qian, H Ausserwoger, T Sneideris, M Farag, RV Pappu, TPJ Knowles
– Proceedings of the National Academy of Sciences of the United States of America
(2024)
121,
e2407453121
(doi: 10.1073/pnas.2407453121)
Synapsin condensation is governed by sequence-encoded molecular grammars
C Hoffmann, KM Ruff, IA Edu, MK Shinn, JV Tromm, MR King, A Pant, H Ausserwöger, JR Morgan, TPJ Knowles, RV Pappu, D Milovanovic
(2024)
(doi: 10.1101/2024.08.03.606464)
Assessment of Fine-Tuned Large Language Models for Real-World Chemistry and Material Science Applications
J van Herck, MV Gil, KM Jablonka, A Abrudan, A Anker, M Asgari, B Blaiszik, L Choudhury, C Corminboeuf, H Daglar, IT Foster, S Garcia, M Garvin, G Godin, LL Good, J Gu, NX Hu, X Jin, T Junkers, S Keskin, TPJ Knowles, R Laplaza, S Majumdar, H Mashhadimoslem, RD McIntosh, SM Moosavi, B Mourino, F Nerli, C Pevida, N Poudineh, M Rajabi-Kochi, KL Saar, FH Saboor, M Sagharichiha, KJ Schmidt, J Shi, D Svatunek, M Taddei, I Tetko, D Tolnai, S Vahdatifar, J Whitmer, F Wieland, R Willumeit-Romer, A Zuttel, B Smit
(2024)
(doi: 10.26434/chemrxiv-2024-mm31v)
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers.
J Nielsen, J Lauritsen, JN Pedersen, JS Nowak, MK Bendtsen, G Kleijwegt, K Lusser, LC Pitarch, JV Moreno, MM Schneider, G Krainer, L Goksøyr, P Khalifé, SS Kaalund, S Aznar, M Kjærgaard, V Sereikaité, K Strømgaard, TPJ Knowles, MA Nielsen, AF Sander, M Romero-Ramos, DE Otzen
– npj Parkinson's Disease
(2024)
10,
139
(doi: 10.1038/s41531-024-00747-6)
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, L-M Needham, R Peters, SF Lee, K O’Holleran
(2024)
(doi: 10.1101/2024.07.18.604091)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
– Nature Communications
(2024)
15,
5418
(doi: 10.1038/s41467-024-48496-7)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition.
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
– Nature communications
(2024)
15,
5418
(doi: 10.1038/s41467-024-48496-7)
Thermodynamic profiles for cotranslational trigger factor substrate recognition
TW Herling, AME Cassaignau, AS Wentink, QAE Peter, PC Kumar, T Kartanas, MM Schneider, LD Cabrita, J Christodoulou, TPJ Knowles
– Sci Adv
(2024)
10,
eadn4824
(doi: 10.1126/sciadv.adn4824)
Improved Imaging Surface for Quantitative Single-Molecule Microscopy
YP Zhang, E Lobanova, A Dworkin, M Furlepa, WS Yang, M Burke, JX Meng, N Potter, RL Sala, L Kahanawita, F Layburn, OA Scherman, CH Williams-Gray, D Klenerman
– ACS Applied Materials and Interfaces
(2024)
16,
37255
(doi: 10.1021/acsami.4c06512)
Biomolecular condensates are characterized by interphase electric potentials
AE Posey, A Bremer, NA Erkamp, A Pant, TPJ Knowles, Y Dai, T Mittag, RV Pappu
(2024)
(doi: 10.1101/2024.07.02.601783)
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
G Šneiderienė, MA Czekalska, CK Xu, AK Jayaram, G Krainer, WE Arter, QAE Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
– ACS Nano
(2024)
18,
17469
(doi: 10.1021/acsnano.3c10889)
Hierarchical Protofilament Intertwining Rules the Formation of Mixed-Curvature Amyloid Polymorphs
J Zhou, S Assenza, M Tatli, J Tian, IM Ilie, EL Starostin, A Caflisch, TPJ Knowles, G Dietler, FS Ruggeri, H Stahlberg, SK Sekatskii, R Mezzenga
– Advanced Science
(2024)
11,
e2402740
(doi: 10.1002/advs.202402740)

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