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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 181 - 200 of 1105 publications
Selenium Silk Nanostructured Films with Antifungal and Antibacterial Activity.
Z Toprakcioglu, EG Wiita, AK Jayaram, RC Gregory, TPJ Knowles
– ACS Applied Materials & Interfaces
(2023)
15,
10452
Non-specificity fingerprints for clinical stage antibodies in solution
T Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, T Knowles
(2023)
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, A Klymchenko, S Davis, E Paluch, D Klenerman, M Lew, K O’Holleran, S Lee
(2023)
Multiphase condensates from a kinetically arrested phase transition
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
– Nature communications
(2023)
14,
684
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
– Nature communications
(2023)
14,
653
Bioprinting microporous functional living materials from protein-based core-shell microgels
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
– Nat Commun
(2023)
14,
322
Enhanced surface nanoanalytics of transient biomolecular processes
AM Miller, S Chia, Z Toprakcioglo, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, T Knowles
– Science advances
(2023)
9,
eabq3151
Label-free detection of proteins with optofluidic hollow-core photonic crystal fibre sensors
JR Heck, E Miele, R Mouthaan, MH Frosz, TPJ Knowles, TG Euser
– Proceedings of SPIE--the International Society for Optical Engineering
(2023)
12327,
1232709-1232709-6
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation
KN Baumann, G Šneiderienė, M Sanguanini, M Schneider, O Rimon, A González Díaz, H Greer, D Thacker, S Linse, TPJ Knowles, M Vendruscolo
– ACS Chem Neurosci
(2022)
14,
323
Perphenazine–Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, X Jiang, AH Kwan, ADJ McKenzie, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
– ACS Chem Neurosci
(2022)
14,
87
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, PS George-Hyslop, S Alberti, TPJ Knowles
– Nature Communications
(2022)
13,
7845
Microfluidics for multiscale studies of biomolecular condensates.
NA Erkamp, R Qi, TJ Welsh, TPJ Knowles
– Lab on a Chip
(2022)
23,
9
Selenium Silk Nanostructured Films for Antifungal and Antibacterial Treatments
Z Toprakcioglu, E Wiita, A Jayaram, R Gregory, T Knowles
(2022)
The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus.
H Zhu, M Narita, JA Joseph, G Krainer, WE Arter, I Olan, KL Saar, N Ermann, JR Espinosa, Y Shen, MA Kuri, R Qi, TJ Welsh, R Collepardo-Guevara, M Narita, TPJ Knowles
– ChemBioChem
(2022)
24,
e202200450
Core-Shell Spheroid-Laden Microgels Crosslinked under Biocompatible Conditions for Probing Cancer-Stromal Communication
H Zhu, LWY Roode, AJ Parry, NA Erkamp, M Rodriguez-Garcia, M Narita, Y Shen, Y Ou, Z Toprakcioglu, M Narita, TPJ Knowles
– Advanced NanoBiomed Research
(2022)
2,
2200138
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration.
S Fiedler, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, M Emmenegger, V Kosmoliaptsis, ES Theel, JR Mills, AM Sholukh, A Aguzzi, A Iwasaki, AK Lynn, TPJ Knowles
– Sci Rep
(2022)
12,
19791
Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α‑Synuclein Aggregates
S Chia, Z Faidon Brotzakis, RI Horne, A Possenti, B Mannini, R Cataldi, M Nowinska, R Staats, S Linse, TPJ Knowles, J Habchi, M Vendruscolo
– Molecular pharmaceutics
(2022)
20,
183
Non-specificity as the sticky problem in therapeutic antibody development.
H Ausserwöger, MM Schneider, TW Herling, P Arosio, G Invernizzi, TPJ Knowles, N Lorenzen
– Nat Rev Chem
(2022)
6,
844
Microscale Diffusiophoresis of Proteins.
QAE Peter, RPB Jacquat, TW Herling, PK Challa, T Kartanas, TPJ Knowles
– J Phys Chem B
(2022)
126,
8913
Multi-dimensional protein solubility optimization with an ultra-high-throughput microfluidic platform
N Erkamp, M Oeller, T Sneideris, H Ausserwӧger, A Levin, T Welsh, R Qi, D Qian, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
(2022)