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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 901 - 920 of 1104 publications
Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
– PLoS Computational Biology
(2011)
7,
e1002169
Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
– Biophys J
(2011)
101,
1681
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV MacPherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
– Angewandte Chemie - International Edition
(2011)
50,
9638
Imaging and characterisation of the surface of live cells
D Klenerman, YE Korchev, SJ Davis
– Current Opinion in Chemical Biology
(2011)
15,
696
Quantum dot photoluminescence activation and decay: dark, bright, and reversible populations in ZnS-capped CdSe nanocrystals
MA Osborne, SF Lee
– ACS Nano
(2011)
5,
8295
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– International Journal of Molecular Sciences
(2011)
12,
5844
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– International Journal of Molecular Sciences
(2011)
12,
5844
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces.
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV Macpherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
– Angew Chem Int Ed Engl
(2011)
50,
9638
Observation of spatial propagation of amyloid assembly from single nuclei.
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
– Proceedings of the National Academy of Sciences
(2011)
108,
14746
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
– J Am Chem Soc
(2011)
133,
14160
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– Journal of Chemical Physics
(2011)
135,
065106
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
– Journal of Chemical Physics
(2011)
135,
065105
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
– Journal of Molecular Biology
(2011)
411,
329
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– Journal of Chemical Physics
(2011)
135,
065107
Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders
M Vendruscolo, TPJ Knowles, CM Dobson
– Cold Spring Harbor perspectives in biology
(2011)
3,
a010454
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
90
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
215
Nanomechanics of functional and pathological amyloid materials.
TPJ Knowles, MJ Buehler
– Nature Nanotechnology
(2011)
6,
469
Separation and detection of bacteria using rupture event scanning
MA Cooper, FN Dultsev, VP Ostanin, D Klenerman
– Analytica Chimica Acta
(2011)
702,
233
The T Cell Receptor Triggering Apparatus Is Composed of Monovalent or Monomeric Proteins
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, P Nilsson, DL Sleep, CM Gonçalves, SH Morgan, JH Felce, R Mahen, RA Fernandes, AM Carmo, D Klenerman, SJ Davis
– Journal of Biological Chemistry
(2011)
286,
31993