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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 901 - 920 of 1101 publications
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– International Journal of Molecular Sciences
(2011)
12,
5844
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– International Journal of Molecular Sciences
(2011)
12,
5844
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces.
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV Macpherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
– Angew Chem Int Ed Engl
(2011)
50,
9638
Observation of spatial propagation of amyloid assembly from single nuclei.
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
– Proceedings of the National Academy of Sciences of the United States of America
(2011)
108,
14746
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
– J Am Chem Soc
(2011)
133,
14160
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– J Chem Phys
(2011)
135,
065107
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– The Journal of Chemical Physics
(2011)
135,
065106
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
– J Chem Phys
(2011)
135,
065105
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
– Journal of Molecular Biology
(2011)
411,
329
Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders
M Vendruscolo, TPJ Knowles, CM Dobson
– Cold Spring Harb Perspect Biol
(2011)
3,
a010454
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
215
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
90
Nanomechanics of functional and pathological amyloid materials
TPJ Knowles, MJ Buehler
– Nat Nanotechnol
(2011)
6,
469
Separation and detection of bacteria using rupture event scanning.
MA Cooper, FN Dultsev, VP Ostanin, D Klenerman
– Anal Chim Acta
(2011)
702,
233
The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, P Nilsson, DL Sleep, CM Gonçalves, SH Morgan, JH Felce, R Mahen, RA Fernandes, AM Carmo, D Klenerman, SJ Davis
– J Biol Chem
(2011)
286,
31993
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
– Alzheimer's & Dementia
(2011)
7,
e21
Conserved C-Terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-Synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
– J Mol Biol
(2011)
411,
329
Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions
SL Shammas, TPJ Knowles, AJ Baldwin, CE Macphee, ME Welland, CM Dobson, GL Devlin
– Biophysical journal
(2011)
100,
2783
Probing protein aggregation with quartz crystal microbalances.
TPJ Knowles, GL Devlin, CM Dobson, ME Welland
– Methods Mol Biol
(2011)
752,
137