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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 901 - 920 of 1100 publications
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– International Journal of Molecular Sciences
(2011)
12,
5844
Multifunctional Nanoprobes for Nanoscale Chemical Imaging and Localized Chemical Delivery at Surfaces and Interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV Macpherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
– Angew Chem Int Ed Engl
(2011)
50,
9638
Observation of spatial propagation of amyloid assembly from single nuclei.
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
– Proceedings of the National Academy of Sciences of the United States of America
(2011)
108,
14746
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
– Journal of the American Chemical Society
(2011)
133,
14160
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– The Journal of Chemical Physics
(2011)
135,
065107
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– The Journal of chemical physics
(2011)
135,
065106
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
– The Journal of chemical physics
(2011)
135,
065105
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
– Journal of Molecular Biology
(2011)
411,
329
Protein solubility and protein homeostasis: a generic view of protein misfolding disorders.
M Vendruscolo, TPJ Knowles, CM Dobson
– Cold Spring Harbor Perspectives in Biology
(2011)
3,
a010454
Direct observation of the interconversion of normal and pathogenic forms of alpha-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
215
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40,
90
Nanomechanics of functional and pathological amyloid materials.
TPJ Knowles, MJ Buehler
– Nature nanotechnology
(2011)
6,
469
Separation and detection of bacteria using rupture event scanning
MA Cooper, FN Dultsev, VP Ostanin, D Klenerman
– Analytica Chimica Acta
(2011)
702,
233
The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins.
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, P Nilsson, DL Sleep, CM Gonçalves, SH Morgan, JH Felce, R Mahen, RA Fernandes, AM Carmo, D Klenerman, SJ Davis
– Journal of Biological Chemistry
(2011)
286,
31993
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
– Alzheimer's & Dementia
(2011)
7,
e21
Conserved C-Terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-Synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
– Journal of molecular biology
(2011)
411,
329
Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions.
SL Shammas, TPJ Knowles, AJ Baldwin, CE Macphee, ME Welland, CM Dobson, GL Devlin
– Biophysical Journal
(2011)
100,
2783
Probing Protein Aggregation with Quartz Crystal Microbalances
TPJ Knowles, GL Devlin, CM Dobson, ME Welland
– Methods in Molecular Biology
(2011)
752,
137
Realizing The Biological and Biomedical Potential of Nanoscale Imaging Using A Pipette Probe
AI Shevchuk, P Novak, Y Takahashi, R Clarke, M Miragoli, B Babakinejad, J Gorelik, YE Korchev, D Klenerman
– Nanomedicine
(2011)
6,
565