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  • Currently displaying 621 - 640 of 1107 publications
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers.
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
– The Journal of Chemical Physics
(2017)
146,
135102
(doi: 10.1063/1.4977932)
PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations.
AA Janeczek, E Scarpa, MH Horrocks, RS Tare, CA Rowland, D Jenner, TA Newman, RO Oreffo, SF Lee, ND Evans
– Nanomedicine
(2017)
12,
845
(doi: 10.2217/nnm-2016-0386)
Exciton Coupling of Phenylalanine Reveals Conformational Changes of Cationic Peptides
C Bortolini, L Liu, SV Hoffmann, NC Jones, TPJ Knowles, M Dong
– ChemistrySelect
(2017)
2,
2476
(doi: 10.1002/slct.201601916)
3D structures of individual mammalian genomes studied by single-cell Hi-C.
TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, KJ Wohlfahrt, W Boucher, A O’Shaughnessy-Kirwan, J Cramard, AJ Faure, M Ralser, E Blanco, L Morey, M Sanso, MGS Palayret, B Lehner, L Di Croce, A Wutz, B Hendrich, D Klenerman, ED Laue
– Nature
(2017)
544,
59
(doi: 10.1038/nature21429)
Inhibition of α‑Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α‑Synuclein Species
FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, TPJ Knowles, M Vendruscolo, CM Dobson, N Cremades
– Biochemistry
(2017)
56,
1177
(doi: 10.1021/acs.biochem.6b01178)
Correction for: A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (E1009-E1017) DOI: 10.1073/pnas.1610586114)
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Mueller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
– Proceedings of the National Academy of Sciences of the United States of America
(2017)
114,
e2543
(doi: 10.1073/pnas.1701964114)
Acceleration of α-synuclein aggregation
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
– Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
(2017)
24,
20
(doi: 10.1080/13506129.2017.1292904)
Physical principles of filamentous protein self-assembly kinetics.
TCT Michaels, LX Liu, G Meisl, TPJ Knowles
– Journal of Physics Condensed Matter
(2017)
29,
153002
(doi: 10.1088/1361-648X/aa5f10)
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
– Proceedings of the National Academy of Sciences
(2017)
114,
E1009
(doi: 10.1073/pnas.1610586114)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
– Biophysical Journal
(2017)
112,
494A
(doi: 10.1016/j.bpj.2016.11.2673)
Direct Modulation of the Mitochondrial Permeability Transition Pore by Oligomeric Alpha-Synuclein Causes Toxicity in PD
M Ludtmann, P Angelova, M-L Choi, M Horrocks, A Baev, D Little, M Devine, P Gissen, E Pavlov, D Klenerman, A Abramov, S Gandhi
– Biophysical Journal
(2017)
112,
440A
(doi: 10.1016/j.bpj.2016.11.2351)
Imaging the early events of T-cell triggering
D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S108
(link to publication)
Measuring the prion-like character of tau by TIRF microscopy
F Kundel, B Falcon, L Hong, N Esteras, AJ Dear, AY Abramov, TPJ Knowles, M Goedert, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S240
(link to publication)
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning
PK Challa, T Kartanas, J Charmet, TPJ Knowles
– Biomicrofluidics
(2017)
11,
014113
(doi: 10.1063/1.4976690)
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
– Lab on a Chip - Miniaturisation for Chemistry and Biology
(2017)
18,
162
(doi: 10.1039/c7lc00797c)
Size dependent structure and effects of amyloid beta42
D Wirthensohn, F Kundel, S De, C Hughes, MH Horrocks, P Flagmeier, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S242
(link to publication)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S68
(link to publication)
A microfluidic platform for quantitative protein studies
TW Herling, P Arosio, T Mueller, DJ O'Connell, MC Bauer, J Persson, U Weininger, S Linse, TPJ Knowles
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S345
(link to publication)
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S348
(link to publication)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S236
(link to publication)

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