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  • Currently displaying 561 - 580 of 1099 publications
Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation.
TCT Michaels, A Šarić, J Habchi, S Chia, G Meisl, M Vendruscolo, CM Dobson, TPJ Knowles
– Annual Review of Physical Chemistry
(2018)
69,
1
(doi: 10.1146/annurev-physchem-050317-021322)
Real-Time Intrinsic Fluorescence Visualization and Sizing of Proteins and Protein Complexes in Microfluidic Devices
PK Challa, Q Peter, MA Wright, Y Zhang, KL Saar, JA Carozza, JLP Benesch, TPJ Knowles
– Analytical Chemistry
(2018)
90,
3849
(doi: 10.1021/acs.analchem.7b04523)
Additional contributions from: Nobel Symposium 162 - Microfluidics
S Löfås, AE Herr, J Qin, T Knowles, T Kitamori, H Lu, DJ Beebe, J Han, J Landers, A Manz, R Zengerle, DA Weitz, J Elf, T Laurell
(2018)
(doi: 10.48550/arxiv.1802.08565)
Maximizing the field of view and accuracy in 3D Single Molecule Localization Microscopy.
SA Rehman, AR Carr, MO Lenz, SF Lee, K O'Holleran
– Optics Express
(2018)
26,
4631
(doi: 10.1364/OE.26.004631)
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions
H Gang, C Galvagnion, G Meisl, T Müller, M Pfammatter, AK Buell, A Levin, CM Dobson, B Mu, TPJ Knowles
– Analytical chemistry
(2018)
90,
3284
(doi: 10.1021/acs.analchem.7b04820)
Detecting RNA base methylations in single cells by in situ hybridization
RT Ranasinghe, MR Challand, KA Ganzinger, BW Lewis, C Softley, WH Schmied, MH Horrocks, N Shivji, JW Chin, J Spencer, D Klenerman
– Nat Commun
(2018)
9,
655
(doi: 10.1038/s41467-017-02714-7)
Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2
J Yang, AJ Dear, TCT Michaels, CM Dobson, TPJ Knowles, S Wu, S Perrett
– J Am Chem Soc
(2018)
140,
2493
(doi: 10.1021/jacs.7b10439)
2-Photon Lithography for Nanofluidic Lab-on-Chip Devices
O Vanderpoorten, PK Challa, Q Peter, J Charmet, N Curry, TPJ Knowles, CF Kaminski
– Biophysical Journal
(2018)
114,
689a
(doi: 10.1016/j.bpj.2017.11.3716)
Revealing the Mechanism of Amyloid Fibril Formation by Combined Single Molecule FRET and Kinetic Modeling
J Yang, AJ Dear, TCT Michaels, CM Dobson, TPJ Knowles, S Perretti, S Wu
– Biophysical Journal
(2018)
114,
685a
(doi: 10.1016/j.bpj.2017.11.3693)
Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease
S Chia, J Habchi, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Biophysical Journal
(2018)
114,
225a
(doi: 10.1016/j.bpj.2017.11.1253)
Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates
R Limbocker, B Mannini, S Chia, FS Ruggeri, M Perni, R Cascella, C Xu, J Habchi, JR Kumita, F Chiti, TPJ Knowles, M Vendruscolo, CM Dobson
– Biophysical Journal
(2018)
114,
430A
(doi: 10.1016/j.bpj.2017.11.2382)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Ghandi, SE Bohndiek, TN Snaddon, SF Lee
– R Soc Open Sci
(2018)
5,
171399
(doi: 10.1098/rsos.171399)
Molecular Mechanism of AB42 Peptide-Fibril Adsorption
MMJ Bellaiche, TPJ Knowles, RB Best
– Biophysical Journal
(2018)
114,
208a
(doi: 10.1016/j.bpj.2017.11.1165)
Probing the Interaction of ABETA42 Amyloid Species with an Aggregation Suppressor Molecule by Infrared Nanospectroscopy
FS Ruggeri, J Habchi, S Chia, M Vendruscolo, TPJ Knowles
– Biophysical Journal
(2018)
114,
224A
(doi: 10.1016/j.bpj.2017.11.1246)
Activation of toll-like receptors nucleates assembly of the MyDDosome signaling hub
SL Latty, J Sakai, L Hopkins, B Verstak, T Paramo, NA Berglund, E Cammarota, P Cicuta, NJ Gay, PJ Bond, D Klenerman, CE Bryant
– eLife
(2018)
7,
e31377
(doi: 10.7554/elife.31377)
Optical Structural Analysis of Individual α-Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
– Angew Chem Int Ed Engl
(2018)
57,
4886
(doi: 10.1002/anie.201710779)
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
– Chem Sci
(2018)
9,
3503
(doi: 10.1039/c7sc04331g)
Enhancing power density of biophotovoltaics by decoupling storage and power delivery
KL Saar, P Bombelli, DJ Lea-Smith, T Call, EM Aro, T Müller, CJ Howe, TPJ Knowles
– Nature Energy
(2018)
3,
75
(doi: 10.1038/s41560-017-0073-0)
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
– Chemical Communications
(2018)
54,
8667
(doi: 10.1039/c8cc02204f)
Microfluidic Diffusional Sizing Enables Characterisation of Protein-Protein Interactions Under Native Conditions
S Devenish, C Thorne, T Scheidt, J Carozza, P Arosio, Y Zhang, A Buell, T Mueller, A Lynn, J Faherty, M Wright, M Butz, T Knowles
– PROTEIN SCIENCE
(2018)
27,
167
(link to publication)

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