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  • Currently displaying 521 - 540 of 1099 publications
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing.
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
– Analytical chemistry
(2018)
90,
10302
(doi: 10.1021/acs.analchem.8b02051)
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
– J Neurosci Methods
(2018)
306,
57
(doi: 10.1016/j.jneumeth.2018.02.005)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
– Biochemistry
(2018)
57,
4891
(doi: 10.1021/acs.biochem.8b00353)
Enhancing the Resolution of Micro Free Flow Electrophoresis through Spatially Controlled Sample Injection.
KL Saar, T Müller, J Charmet, PK Challa, TPJ Knowles
– Anal Chem
(2018)
90,
8998
(doi: 10.1021/acs.analchem.8b01205)
O2‐02‐02: TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES
FA Aprile, P Sormanni, M Perni, P Arosio, R Limbocker, S Chhangur, B Mannini, S Linse, T Knowles, CM Dobson, M Vendruscolo
– Alzheimer's & Dementia
(2018)
14,
p611
(doi: 10.1016/j.jalz.2018.06.2646)
Fabrication of Scaffold-Based 3D Magnetic Nanowires for Domain Wall Applications
D Sanz-Hernández, RF Hamans, J Osterrieth, J-W Liao, L Skoric, JD Fowlkes, PD Rack, A Lippert, SF Lee, R Lavrijsen, A Fernández-Pacheco
– Nanomaterials (Basel)
(2018)
8,
483
(doi: 10.3390/nano8070483)
Determination of Polypeptide Conformation with Nanoscale Resolution in Water.
G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone
– ACS nano
(2018)
12,
6612
(doi: 10.1021/acsnano.8b01425)
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
– ACS chemical biology
(2018)
13,
2308
(doi: 10.1021/acschembio.8b00466)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
– Nature Communications
(2018)
9,
2520
(doi: 10.1038/s41467-018-04486-0)
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils.
FS Ruggeri, F Benedetti, TPJ Knowles, HA Lashuel, S Sekatskii, G Dietler
– Proc Natl Acad Sci U S A
(2018)
115,
7230
(doi: 10.1073/pnas.1721220115)
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
– Cell reports
(2018)
23,
3492
(doi: 10.1016/j.celrep.2018.05.074)
Origin of metastable oligomers and their effects on amyloid fibril self- assembly
F Hasecke, T Miti, C Perez, J Barton, D Schölzel, L Gremer, CSR Grüning, G Matthews, G Meisl, TPJ Knowles, D Willbold, P Neudecker, H Heise, G Ullah, W Hoyer, M Muschol
– Chemical science
(2018)
9,
5937
(doi: 10.1039/c8sc01479e)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
– Nature Communications
(2018)
9,
2293
(doi: 10.1038/s41467-018-04422-2)
On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations
X Yang, G Meisl, B Frohm, E Thulin, TPJ Knowles, S Linse
– Proceedings of the National Academy of Sciences
(2018)
115,
e5849
(doi: 10.1073/pnas.1803539115)
Kinetic analysis of amyloid formation
G Meisl, TCT Michaels, S Linse, TPJ Knowles
– Methods in Molecular Biology
(2018)
1779,
181
(doi: 10.1007/978-1-4939-7816-8_12)
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Y Song, TCT Michaels, Q Ma, Z Liu, H Yuan, S Takayama, TPJ Knowles, HC Shum
– Nature Communications
(2018)
9,
2110
(doi: 10.1038/s41467-018-04510-3)
Cooperative Assembly of Hsp70 Subdomain Clusters.
MA Wright, FA Aprile, MMJ Bellaiche, TCT Michaels, T Müller, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
– Biochemistry
(2018)
57,
3641
(doi: 10.1021/acs.biochem.8b00151)
Reaction rate theory for supramolecular kinetics: application to protein aggregation
TCT Michaels, LX Liu, S Curk, PG Bolhuis, A Šarić, TPJ Knowles
– Molecular Physics
(2018)
116,
3055
(doi: 10.1080/00268976.2018.1474280)
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH.
IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
– Chem Sci
(2018)
9,
5506
(doi: 10.1039/c8sc01109e)
Rapid Growth of Acetylated Aβ(16-20) into Macroscopic Crystals.
C Bortolini, LH Klausen, SV Hoffmann, NC Jones, D Saadeh, Z Wang, TPJ Knowles, M Dong
– ACS nano
(2018)
12,
5408
(doi: 10.1021/acsnano.8b00448)

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