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  • Currently displaying 41 - 60 of 992 publications
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
(2023)
(doi: 10.21203/rs.3.rs-3252197/v1)
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
M Vendruscolo, S Dada, Z Toprakcioglu, M Hardenberg, M Cali, L Mrugalla, O Morris, A Roentgen, T Knowles
(2023)
(doi: 10.21203/rs.3.rs-3174399/v1)
Ganglioside Lipids Inhibit the Aggregation of the Alzheimer’s Related Peptide Amyloid-β
Z Toprakcioglu, A Jayaram, T Knowles
(2023)
(doi: 10.1101/2023.09.10.556751)
Effects of Processing-Induced Contamination on Organic Electronic Devices.
D Simatos, IE Jacobs, I Dobryden, M Nguyen, A Savva, D Venkateshvaran, M Nikolka, J Charmet, LJ Spalek, M Gicevičius, Y Zhang, G Schweicher, DJ Howe, S Ursel, J Armitage, IB Dimov, U Kraft, W Zhang, M Alsufyani, I McCulloch, RM Owens, PM Claesson, TPJ Knowles, H Sirringhaus
– Small Methods
(2023)
7,
e2300476
(doi: 10.1002/smtd.202300476)
Thermodynamic profiles for co-translational trigger factor function
T Herling, A Cassaignau, A Wentink, Q Peter, P Kumar, T Kartanas, M Schneider, L Cabrita, J Christodoulou, T Knowles
(2023)
(doi: 10.1101/2023.08.23.554456)
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
(2023)
(doi: 10.1101/2023.08.11.552963)
The liquid-to-solid transition of FUS is promoted by the condensate surface
Y Shen, A Chen, W Wang, Y Shen, FS Ruggeri, S Aime, Z Wang, S Qamar, JR Espinosa, A Garaizar, P St George-Hyslop, R Collepardo-Guevara, DA Weitz, D Vigolo, TPJ Knowles
– Proceedings of the National Academy of Sciences of the United States of America
(2023)
120,
e2301366120
(doi: 10.1073/pnas.2301366120)
Electrophysiological In Vitro Study of Long-Range Signal Transmission by Astrocytic Networks
N Hastings, Y-L Yu, B Huang, S Middya, M Inaoka, NA Erkamp, RJ Mason, A Carnicer-Lombarte, S Rahman, TPJ Knowles, M Bance, GG Malliaras, MRN Kotter
– Adv Sci (Weinh)
(2023)
10,
2301756
(doi: 10.1002/advs.202301756)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, M Schneider, T Welsh, J Fan, Q Peter, E Andrzejewska, G Šneiderienė, M Czekalska, H Ausserwoeger, L Chai, W Arter, K Saar, T Herling, T Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, S Lee, TPJ Knowles
(2023)
(doi: 10.1101/2023.07.12.548675)
Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, T Michaels, T Knowles, A Šarić
(2023)
(doi: 10.1101/2023.07.05.547777)
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
E Dimou, T Katsinelos, G Meisl, BJ Tuck, S Keeling, AE Smith, E Hidari, JYL Lam, M Burke, S Lövestam, RT Ranasinghe, WA McEwan, D Klenerman
– Cell Rep
(2023)
42,
112725
(doi: 10.1016/j.celrep.2023.112725)
Amyloid formation as a protein phase transition
TCT Michaels, D Qian, A Šarić, M Vendruscolo, S Linse, TPJ Knowles
– Nature Reviews Physics
(2023)
5,
379
(doi: 10.1038/s42254-023-00598-9)
Amyloids and protein aggregation.
S Linse, T Knowles
– Chem Sci
(2023)
14,
6491
(doi: 10.1039/d2sc90225g)
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
– Cell Syst
(2023)
14,
464
(doi: 10.1016/j.cels.2023.05.003)
Formation of Protein Nanoparticles in Microdroplet Flow Reactors
Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo, X Wang, TPJ Knowles
– ACS nano
(2023)
17,
11335
(doi: 10.1021/acsnano.3c00107)
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
– The Journal of Infectious Diseases
(2023)
228,
723
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
– Proceedings of the National Academy of Sciences
(2023)
120,
e2216234120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
– Chemical reviews
(2023)
123,
8988
(doi: 10.1021/acs.chemrev.2c00586)
High-density volumetric super-resolution microscopy
S Daly, JF Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, J Beckwith, E Sanders, R Sims, D Klenerman, S Davis, K O’Holleran, S Lee
(2023)
(doi: 10.1101/2023.05.02.539032)

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