skip to content
Home

Yusuf Hamied Department of Chemistry

 

Publications by Dr Paul Barker

Fluorogenic, Subsingle-Turnover Monitoring of Enzymatic Reactions Involving NAD(P)H Provides a Generalized Platform for Directed Ultrahigh-Throughput Evolution of Biocatalysts in Microdroplets
M Penner, OJ Klein, M Gantz, FEH Nintzel, A-C Prowald, S Boss, P Barker, P Dupree, F Hollfelder
– J Am Chem Soc
(2025)
147,
10903
(DOI: 10.1021/jacs.4c11804)
Combining experiment and energy landscapes to explore anaerobic heme breakdown in multifunctional hemoproteins.
AD Keith, EB Sawyer, DCY Choy, Y Xie, GS Biggs, OJ Klein, PD Brear, DJ Wales, PD Barker
– Physical chemistry chemical physics : PCCP
(2024)
26,
695
(DOI: 10.1039/d3cp03897a)
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation
GS Biggs, OJ Klein, SL Maslen, JM Skehel, TJ Rutherford, SMV Freund, F Hollfelder, SR Boss, PD Barker
– Angewandte Chemie (International ed. in English)
(2021)
60,
10919
(DOI: 10.1002/anie.202015834)
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation
GS Biggs, OJ Klein, SL Maslen, JM Skehel, TJ Rutherford, SMV Freund, F Hollfelder, SR Boss, PD Barker
– Angewandte Chemie
(2021)
133,
11014
(DOI: 10.1002/ange.202015834)
Unlocking the Full Evolutionary Potential of Artificial Metalloenzymes Through Direct Metal-Protein Coordination
GS Biggs, OJ Klein, SR Boss, PD Barker
– Johnson Matthey Technology Review
(2020)
64,
407
(DOI: 10.1595/205651320x15928204097766)
Guest Editorial: Breaking Down Barriers and Borrowing from Biology
T Sturgeon, Y Yan, R Zhu, S Li, GS Biggs, OJ Klein, SR Boss, PD Barker, I Turetgen, MJ Haskew, JG Hardy, B Yilmaz, HA Karavana, T Tuccar, E Ilhan-Sungur, G Muyzer, B Candiroglu, ND Gungor, D Berber, I Turkmenoglu, NC Sesal, M Birbir, P Caglayan, Y Birbir, G Altug, M Cardak, PSC Turetken, S Kalkan, S Gurun, M Hayes, S Staniland, T Angelini, A Pushpanath, A Bornadel, E Siirola, S Bisagni, A Zanotti-Gerosa, B Dominguez
– Johnson Matthey Technology Review
(2020)
64,
394
(DOI: 10.1595/205651320x15954136194837)
Use of a fluorinated probe to quantitatively monitor amino acid binding preferences of ruthenium( ii ) arene complexes
GS Biggs, MJ O'Neill, P Carames Mendez, TG Scrase, Y Lin, AM Bin-Maarof, AD Bond, SR Boss, PD Barker
– Dalton transactions (Cambridge, England : 2003)
(2019)
48,
6910
(DOI: 10.1039/c8dt05159c)
Synthesis and extensive characterisation of phosphorus doped graphite
PD Matthews, TC King, H Glass, PCMM Magusin, GJ Tustin, PAC Brown, JA Cormack, R García-Rodríguez, M Leskes, SE Dutton, PD Barker, FM Grosche, A Alavi, CP Grey, DS Wright
– RSC Advances
(2016)
6,
62140
(DOI: 10.1039/c6ra08639j)
How to make a porphyrin flip: dynamics of asymmetric porphyrin oligomers.
C Shang, JM Philpott, N Bampos, PD Barker, DJ Wales
– Physical chemistry chemical physics : PCCP
(2015)
17,
27094
(DOI: 10.1039/c5cp04636j)
Investigating the Mechanisms of Amylolysis of Starch Granules by Solution-State NMR
AJ Baldwin, DL Egan, FJ Warren, PD Barker, CM Dobson, PJ Butterworth, PR Ellis
– Biomacromolecules
(2015)
16,
1614
(DOI: 10.1021/acs.biomac.5b00190)
Theory and Practice: Bulk Synthesis of C<sub>3</sub>B and its H<sub>2</sub>- and Li-Storage Capacity
TC King, PD Matthews, H Glass, JA Cormack, JP Holgado, M Leskes, JM Griffin, OA Scherman, PD Barker, CP Grey, SE Dutton, RM Lambert, G Tustin, A Alavi, DS Wright
– Angewandte Chemie - International Edition
(2015)
54,
5919
(DOI: 10.1002/anie.201412200)
Selective lability of ruthenium(II) arene amino acid complexes
TG Scrase, MJ O'Neill, AJ Peel, PW Senior, PD Matthews, H Shi, SR Boss, PD Barker
– Inorganic chemistry
(2015)
54,
3118
(DOI: 10.1021/ic502051y)
Folates are potential ligands for ruthenium compounds in vivo
TG Scrase, SM Page, PD Barker, SR Boss
– Dalton Trans.
(2014)
43,
8158
(DOI: 10.1039/c4dt00081a)
Local frustration determines molecular and macroscopic helix structures.
CJ Forman, SN Fejer, D Chakrabarti, PD Barker, DJ Wales
– J Phys Chem B
(2013)
117,
7918
(DOI: 10.1021/jp4040503)
Probing the location of displayed cytochrome b562 on amyloid by scanning tunnelling microscopy
CJ Forman, N Wang, ZY Yang, CG Mowat, S Jarvis, C Durkan, PD Barker
– Nanotechnology
(2013)
24,
175102
(DOI: 10.1088/0957-4484/24/17/175102)
Structural Basis for Efficient Chromophore Communication and Energy Transfer in a Constructed Didomain Protein Scaffold
JAJ Arpino, H Czapinska, A Piasecka, WR Edwards, P Barker, MJ Gajda, M Bochtler, DD Jones
– Journal of the American Chemical Society
(2012)
134,
13632
(DOI: 10.1021/ja301987h)
Continued surprises in the cytochrome c biogenesis story
EB Sawyer, PD Barker
– Protein Cell
(2012)
3,
405
(DOI: 10.1007/s13238-012-2912-x)
The morphology of decorated amyloid fibers is controlled by the conformation and position of the displayed protein
CJ Forman, AA Nickson, SJ Anthony-Cahill, AJ Baldwin, G Kaggwa, U Feber, K Sheikh, SP Jarvis, PD Barker
– ACS Nano
(2012)
6,
1332
(DOI: 10.1021/nn204140a)
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
– Journal of the American Chemical Society
(2011)
133,
14160
(DOI: 10.1021/ja2017703)
Metal and redox selectivity of protoporphyrin binding to the heme chaperone CcmE†
EM Harvat, O Daltrop, F Sobott, M Moreau, PD Barker, JM Stevens, SJ Ferguson
– Metallomics : integrated biometal science
(2011)
3,
363
(DOI: 10.1039/c0mt00085j)

    Study at Cambridge

    About the University

    Research at Cambridge