skip to content

Graduate Admissions

 

Professor Matthew Gaunt

Synthetic Chemistry in the Gaunt Group

Research in our group is centred on organic synthesis and catalysis. We are inspired by the pursuit of new concepts in synthetic organic chemistry involving transition metal catalysis, enantioselective catalysis, protein modification and bioorthogonal chemistry, and total synthesis of natural products and pharmaceuticals. This diverse range of synthesis-driven research areas provides a stimulating and dynamic environment that is enabled by outstanding students and postdocs working at the frontiers of the field. 

We also collaborate with the pharmaceutical industry and other academic groups in Chemical Engineering and Molecular Biology. In this presentation I will outline our over-arching research vision and detail some of the specific areas in which we are currently active.

RELEVANT PAPERS

A General Catalytic β-C−H Carbonylation of Aliphatic Amines to β-Lactams Science 2016, 354, 851.

Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts towards the Synthesis of P-Chiral Phosphines J. Am. Chem. Soc. 2016, 138, 13183.

A Steric Tethering Approach Enables Palladium-Catalysed C-H Activation of Primary Amino Alcohols Nature Chem. 2015, 7, 1009.

Palladium-catalysed C-H activation of aliphatic amines to give strained nitrogen heterocycles Nature 2014, 510, 129.

mjg32@cam.ac.uk
T  01223 336318
www-gaunt.ch.cam.ac.uk