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Postgraduate Admissions

Professor Jonathan Goodman

Synthetic Challenges

Synthetic chemists are very good at making molecules, but synthesis is rarely routine and completely predictable in every detail.

How can we make it easier to design and manufacture new structures? Using all the tools available; experimental, computational, data-handling; we are improving our understanding of chemistry so that selective and high-yielding synthesis becomes more straightforward, and ever more complex and demanding targets become realistic.

Projects in our group include the development of new reactions, focussing on experiment, calculation or both, the automated analysis of analytical data (have we have made what we think we have made?) and the prediction of properties: will a new molecule be safe and stable for as long as we need it to be?

RELEVANT PAPER

Practical Guide for Predicting the Stereochemistry of Bifunctional Phosphoric Acid Catalyzed Reactions of Imines Acc. Chem. Res. 2016, 49, 1029. 

jmg11@cam.ac.uk
T  01223 336434
W  www-jmg.ch.cam.ac.uk