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Yusuf Hamied Department of Chemistry

 

Publications

A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
MA Metrick, NDC Ferreira, E Saijo, A Kraus, K Newell, G Zanusso, M Vendruscolo, B Ghetti, B Caughey
– Acta neuropathologica communications
(2020)
8,
22
Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration (Acta Neuropathologica, (2020), 139, 1, (63-77), 10.1007/s00401-019-02080-2)
E Saijo, MA Metrick, S Koga, P Parchi, I Litvan, S Spina, A Boxer, JC Rojas, D Galasko, A Kraus, M Rossi, K Newell, G Zanusso, LT Grinberg, WW Seeley, B Ghetti, DW Dickson, B Caughey
– Acta Neuropathologica
(2019)
139,
79
Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons.
MA Metrick, N do Carmo Ferreira, E Saijo, AG Hughson, A Kraus, C Orrú, MW Miller, G Zanusso, B Ghetti, M Vendruscolo, B Caughey
– Proc Natl Acad Sci U S A
(2019)
116,
23029
4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration.
E Saijo, MA Metrick, S Koga, P Parchi, I Litvan, S Spina, A Boxer, JC Rojas, D Galasko, A Kraus, M Rossi, K Newell, G Zanusso, LT Grinberg, WW Seeley, B Ghetti, DW Dickson, B Caughey
– Acta Neuropathologica
(2019)
139,
63
Ultrasensitive rt-quic seed amplification assays for disease-associated tau, α-synuclein, and prion aggregates
E Saijo, BR Groveman, A Kraus, M Metrick, CD Orrù, AG Hughson, B Caughey
(2019)
1873,
19
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
A Kraus, E Saijo, MA Metrick, K Newell, CJ Sigurdson, G Zanusso, B Ghetti, B Caughey
– Acta Neuropathologica
(2018)
137,
585
Hofmeister Ion-Induced Changes in Water Structure Correlate with Changes in Solvation of an Aggregated Protein Complex
TP Light, KM Corbett, MA Metrick, G MacDonald
– Langmuir : the ACS journal of surfaces and colloids
(2016)
32,
1360
Variable-Field Analytical Ultracentrifugation: I. Time-Optimized Sedimentation Equilibrium.
J Ma, M Metrick, R Ghirlando, H Zhao, P Schuck
– Biophysical Journal
(2015)
109,
827
Hofmeister ion effects on the solvation and thermal stability of model proteins lysozyme and myoglobin
MA Metrick, G MacDonald
– Colloids and Surfaces A: Physicochemical and Engineering Aspects
(2015)
469,
242
The effects of buffers and pH on the thermal stability, unfolding and substrate binding of RecA.
MA Metrick, JE Temple, G MacDonald
– Biophysical Chemistry
(2013)
184,
29

Research Group

Telephone number

01223 748845

Email address

mam240@cam.ac.uk