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Yusuf Hamied Department of Chemistry

 

Publications

Chemical profiling of DNA G-quadruplex-interacting proteins in live cells
S Balasubramanian, X Zhang, J Spiegel, S Adhikari, S Martinez Cuesta
– Nature Chemistry
(2021)
13,
626
G-quadruplexes are transcription factor binding hubs in human chromatin.
J Spiegel, SM Cuesta, S Adhikari, R Hänsel-Hertsch, D Tannahill, S Balasubramanian
– Genome Biol
(2021)
22,
117
The regulation and functions of DNA and RNA G-quadruplexes.
D Varshney, J Spiegel, K Zyner, D Tannahill, S Balasubramanian
– Nat Rev Mol Cell Biol
(2020)
21,
459
The structure and function of DNA G-Quadruplexes
S Balasubramanian, S Adhikari, J Spiegel
– Trends Chem
(2019)
2,
123
DNA G-quadruplex structures mold the DNA methylome.
S Balasubramanian, S Mao, A Ghanbarian, J Spiegel, S Martinez Cuesta, D Beraldi, M Di Antonio, R Hansel-Hertsch, D Tannahill
– Nat Struct Mol Biol
(2018)
25,
951
Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
R Hänsel-Hertsch, J Spiegel, G Marsico, D Tannahill, S Balasubramanian
– Nature protocols
(2018)
13,
551
Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase
PM Cromm, J Spiegel, P Küchler, L Dietrich, J Kriegesmann, M Wendt, RS Goody, H Waldmann, TN Grossmann
– ACS chemical biology
(2016)
11,
2375
Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides
PM Cromm, S Schaubach, J Spiegel, A Fürstner, TN Grossmann, H Waldmann
– Nature communications
(2016)
7,
11300
Direct Modulation of Small GTPase Activity and Function
PM Cromm, J Spiegel, TN Grossmann, H Waldmann
– Angewandte Chemie International Edition
(2015)
54,
13516
Hydrocarbon Stapled Peptides as Modulators of Biological Function
PM Cromm, J Spiegel, TN Grossmann
– ACS Chemical Biology
(2015)
10,
1362
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Research Group

Telephone number

01223 762933 (shared)

Email address

js2260@cam.ac.uk