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Department of Chemistry

 
Dr Jade A. McCune completeted her MSci Chemistry (First class Honours) from Queen's University, Belfast (Northern Ireland) followed by her PhD in Chemistry from University of Cambridge. Her PhD research studied the monofunctionalisation of Cucurbit[n]uril macrocycles and their applications as well as the novel solvation of macrocyles in Deep Eutectic Solvents. 

Following this, Dr McCune was awarded an EPSRC KT Fellowship to collaboation with MedImmune (AstraZeneca). Jade developed methodology for the bioconjugation of functionalised Cucurbit[n]uril macrocycles and application of these macrocyclic conjugates in vivo.

Jade has also pioneered the use of deep eutectic solvents for supramolecular chemistry which has been utilised towards small molecule and materials chemistry including the stablisation of highly reactive species such as organic radicals.

Publications

A comparison of choline:urea and choline:oxalic acid deep eutectic solvents at 338 K
M Gilmore, LM Moura, AH Turner, M Swadźba-Kwaśny, SK Callear, JA McCune, OA Scherman, JD Holbrey
– The Journal of Chemical Physics
(2018)
148,
193823
A simple supramolecular assay for drug detection in urine.
S Sonzini, JA McCune, P Ravn, OA Scherman, CF van der Walle
– Chem Commun (Camb)
(2017)
53,
8842
DESolution of CD and CB Macrocycles.
JA McCune, S Kunz, M Olesińska, OA Scherman
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2017)
23,
8601
Modulating the oxidation of cucurbit[n]urils.
JA McCune, E Rosta, OA Scherman
– Organic and Biomolecular Chemistry
(2017)
15,
998

Research Group

Telephone number

01223 336410 (shared)
36420

Email address

jam211@cam.ac.uk