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Yusuf Hamied Department of Chemistry

 

Publications

Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naive Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation
GS Biggs, OJ Klein, SL Maslen, JM Skehel, TJ Rutherford, SMV Freund, F Hollfelder, SR Boss, PD Barker
– Angewandte Chemie - International Edition
(2021)
60,
10919
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation
GS Biggs, OJ Klein, SL Maslen, JM Skehel, TJ Rutherford, SMV Freund, F Hollfelder, SR Boss, PD Barker
– Angewandte Chemie
(2021)
133,
11014
Unlocking the full evolutionary potential of artificial metalloenzymes through direct metal-protein coordination: A review of recent advances for catalyst development
GS Biggs, OJ Klein, SR Boss, PD Barker
– Johnson Matthey Technology Review
(2020)
64,
407
Understanding the Speciation of Ruthenium Arene Complexes as Precursors to Unnatural Enzyme Cofactors
G Biggs
(2020)
Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling
C-C Lin, KM Suen, A Stainthorp, L Wieteska, GS Biggs, A Leitão, CA Montanari, JE Ladbury
– Cancer Lett
(2019)
457,
86
Use of a fluorinated probe to quantitatively monitor amino acid binding preferences of ruthenium(II) arene complexes†
GS Biggs, MJ O'Neill, P Carames Mendez, TG Scrase, Y Lin, AM Bin-Maarof, AD Bond, SR Boss, PD Barker
– Dalton Trans
(2019)
48,
6910

Research Group

Telephone number

01223 336335 (shared)

Email address

gb531@cam.ac.uk

College

Peterhouse