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Department of Chemistry

 

BBSRC CASE Industrial PhD Studentship with AstraZeneca

Project: Protein Aggregation in Ageing

Preclinical testing of passive immunotherapies against amyloid-beta 1-42, a protein strongly implicated with Alzheimer's disease.

Publications

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
– Acta neuropathologica communications
(2019)
7,
120
Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis
CM Henstridge, DI Sideris, E Carroll, S Rotariu, S Salomonsson, M Tzioras, C-A McKenzie, C Smith, CAF von Arnim, AC Ludolph, D Lulé, D Leighton, J Warner, E Cleary, J Newton, R Swingler, S Chandran, TH Gillingwater, S Abrahams, TL Spires-Jones
– Acta Neuropathologica
(2018)
135,
213

Research Group

Email address

dis30@cam.ac.uk