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Department of Chemistry

 

Publications

ThX – a next-generation probe for the early detection of amyloid aggregates
LM Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
– Chemical Science
(2020)
11,
4578
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, B Mannini, J Habchi, TCT Michaels, PK Challa, M Ahn, ST Casford, N Fernando, CK Xu, ND Kloss, SIA Cohen, JR Kumita, C Cecchi, M Zasloff, S Linse, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson
– Nat Commun
(2019)
10,
225
Label-Free Analysis of Protein Aggregation and Phase Behavior
Z Toprakcioglu, P Challa, C Xu, TPJ Knowles
– ACS nano
(2019)
13,
13940
Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.
EA Hubin, A Fay, C Xu, JM Bean, RM Saecker, MS Glickman, SA Darst, EA Campbell
– Elife
(2017)
6,
e22520
siRNA screen identifies QPCT as a druggable target for Huntington's disease.
M Jimenez-Sanchez, W Lam, M Hannus, B Sönnichsen, S Imarisio, A Fleming, A Tarditi, F Menzies, TE Dami, C Xu, E Gonzalez-Couto, G Lazzeroni, F Heitz, D Diamanti, L Massai, VP Satagopam, G Marconi, C Caramelli, A Nencini, M Andreini, GL Sardone, NP Caradonna, V Porcari, C Scali, R Schneider, G Pollio, CJ O'Kane, A Caricasole, DC Rubinsztein
– Nature chemical biology
(2015)
11,
347

Research Group

Telephone number

01223 748844
01223 748845

Email address

cx220@cam.ac.uk