Mass spectrometry for fragment screening.
DS-H Chan, AJ Whitehouse, AG Coyne, C Abell
– Essays Biochem
(2017)
Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines?
RC Panicker, AG Coyne, R Srinivasan
– Current medicinal chemistry
(2017)
24,
Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.
JT Chenge, LV Duyet, S Swami, KJ McLean, ME Kavanagh, AG Coyne, SEJ Rigby, MR Cheesman, HM Girvan, CW Levy, B Rupp, JP von Kries, C Abell, D Leys, AW Munro
– J Biol Chem
(2017)
292,
Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1
ME Kavanagh, J Chenge, A Zoufir, KJ McLean, AG Coyne, A Bender, AW Munro, C Abell
– Biochemistry
(2017)
56,
Corrigendum: Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.
ME Kavanagh, JL Gray, SH Gilbert, AG Coyne, KJ McLean, HJ Davis, AW Munro, C Abell
– ChemMedChem
(2017)
12,
Organic synthesis reactions on-water at the organic-liquid water interface.
RN Butler, AG Coyne
– Org Biomol Chem
(2016)
14,
Fragment-based approaches to TB drugs
C Marchetti, DSH Chan, AG Coyne, C Abell
– Parasitology
(2016)
Insight into Protein Conformation and Subcharging by DMSO from Native Ion Mobility Mass Spectrometry
DS-H Chan, D Matak-Vinkovic, AG Coyne, C Abell
– ChemistrySelect
(2016)
1,
Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.
ME Kavanagh, JL Gray, SH Gilbert, AG Coyne, KJ McLean, HJ Davis, AW Munro, C Abell
– ChemMedChem
(2016)
11,
Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis.
HJ Davis, ME Kavanagh, T Balan, C Abell, AG Coyne
– Bioorg Med Chem Lett
(2016)
26,
