
Publications
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
– Nat Commun
(2021)
12,
143
(DOI: 10.1038/s41467-020-20224-x)
Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis
– ACS infectious diseases
(2020)
6,
2192
(DOI: 10.1021/acsinfecdis.0c00263)
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
– Nucleic Acids Research
(2020)
48,
8099
(DOI: 10.1093/nar/gkaa539)
Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors.
– Journal of medicinal chemistry
(2020)
63,
4749
(DOI: 10.1021/acs.jmedchem.0c00007)
Covalent inactivation of Mycobacterium thermoresistibile inosine-5′-monophosphate dehydrogenase (IMPDH)
– Bioorganic & Medicinal Chemistry Letters
(2020)
30,
126792
(DOI: 10.1016/j.bmcl.2019.126792)
Allosteric small-molecule serine/threonine kinase inhibitors
– Adv Exp Med Biol
(2019)
1163,
253
(DOI: 10.1007/978-981-13-8719-7_11)
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode.
– J Med Chem
(2019)
62,
10586
(DOI: 10.1021/acs.jmedchem.9b01203)
Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility–mass spectrometry
– Biochemical Journal
(2019)
476,
3125
(DOI: 10.1042/BCJ20190318)
Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches
– J Med Chem
(2019)
62,
7210
(DOI: 10.1021/acs.jmedchem.9b00809)
Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.
– Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
(2019)
377,
20180422
(DOI: 10.1098/rsta.2018.0422)
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