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Dr Leila Nahidiazar

PDRA

Leila is a laser physicist and electronic engineer by education who has developed an intense passion for Microscopy in her career path. She has defended her thesis in the field of Cell Biology and Cytoskeletal proteins at the University of Amsterdam. She has used Super Resolution microscopy as her major instrument during her PhD and post Doc studies to study from spacial organization of DNA to Muscle cell physiology. Designing and developing image processing tools have been part of her life as a microscopist. Currently, she is research Associate at the Lee Lab, where scientists try to demystify Parkinson disease by cutting edge knowledge and newly emerging microscopy methods. She is writer and poet in her free times and loves Ski, classic dance and Ice-skatig.

 

Publications

Multicolor Localization-Based Super Resolution Microscopy.
L Nahidiazar, R Harkes
(2021)
2350,
69
(doi: 10.1007/978-1-0716-1593-5_5)
Hemidesmosomes modulate force generation via focal adhesions.
W Wang, A Zuidema, L Te Molder, L Nahidiazar, L Hoekman, T Schmidt, S Coppola, A Sonnenberg
– Journal of Cell Biology
(2020)
219,
e201904137
(doi: 10.1083/jcb.201904137)
Modular actin nano-architecture enables podosome protrusion and mechanosensing.
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A Cambi
– Nat Commun
(2019)
10,
5171
(doi: 10.1038/s41467-019-13123-3)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A cambi
(2019)
(doi: 10.1101/583492)
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices
A Zuidema, W Wang, M Kreft, L Te Molder, L Hoekman, OB Bleijerveld, L Nahidiazar, H Janssen, A Sonnenberg
– J Cell Sci
(2018)
131,
jcs221317
(doi: 10.1242/jcs.221317)
Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation
E Argenzio, J Klarenbeek, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
– The Journal of biological chemistry
(2018)
293,
19161
(doi: 10.1074/jbc.RA118.002779)
CLIC4 is regulated by RhoA-mDia2 signaling through Profilin-1 binding to modulate filopodium length
E Argenzio, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
(2018)
(doi: 10.1101/259259)
Configurations of the Re‐scan Confocal Microscope (RCM) for biomedical applications
GMR DE Luca, E Desclos, RMP Breedijk, L Dolz-Edo, GJ Smits, L Nahidiazar, P Bielefeld, L Picavet, CP Fitzsimons, R Hoebe, EMM Manders
– Journal of Microscopy
(2017)
266,
166
(doi: 10.1111/jmi.12526)
Optimizing imaging conditions for demanding multi-color super resolution localization microscopy
L Nahidiazar, AV Agronskaia, J Broertjes, B van den Broek, K Jalink
– PLoS ONE
(2016)
11,
e0158884
(doi: 10.1371/journal.pone.0158884)
Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway
RH Wijdeven, H Janssen, L Nahidiazar, L Janssen, K Jalink, I Berlin, J Neefjes
– Nat Commun
(2016)
7,
11808
(doi: 10.1038/ncomms11808)
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