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The Abell Group

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  • Currently displaying 1 - 20 of 344 publications
Targeting of fumarate hydratase from Mycobacterium tuberculosis using allosteric inhibitors with a dimeric-binding mode
AJ Whitehouse, MDJ Libardo, M Kasbekar, PD Brear, G Fischer, CJ Thomas, CE Barry, HIM Boshoff, AG Coyne, C Abell
– J Med Chem
(2019)
62,
10586
Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility–mass spectrometry
DS-H Chan, J Hess, E Shaw, C Spry, R Starley, C Dagostin, MVB Dias, R Kale, V Mendes, TL Blundell, AG Coyne, C Abell
– Biochemical Journal
(2019)
476,
3125
Motile Artificial Chromatophores: Light-Triggered Nanoparticles for Microdroplet Locomotion and Color Change
AR Salmon, S Cormier, W Wang, C Abell, JJ Baumberg
– Advanced Optical Materials
(2019)
1900951
Focused surface acoustic waves induced microdroplets generation and its application for microgels
S Jin, X Wei, Z Liu, J Ren, Z Jiang, C Abell, Z Yu
– Sensors and Actuators, B: Chemical
(2019)
291,
1
Development of inhibitors against mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches
AJ Whitehouse, SE Thomas, KP Brown, A Fanourakis, DS-H Chan, MDJ Libardo, V Mendes, HIM Boshoff, RA Floto, C Abell, TL Blundell, AG Coyne
– Journal of Medicinal Chemistry
(2019)
62,
7210
Bioinspired hydrogel microfibres colour-encoded with colloidal crystals
ZJ Meng, J Zhang, X Deng, J Liu, Z Yu, C Abell
– Materials Horizons
(2019)
6,
1938
Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping
SE Thomas, P Collins, RH James, V Mendes, S Charoensutthivarakul, C Radoux, C Abell, AG Coyne, RA Floto, F von Delft, TL Blundell
– Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
(2019)
377,
20180422
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site
B Bestgen, I Krimm, I Kufareva, AAM Kamal, W-G Seetoh, C Abell, RW Hartmann, R Abagyan, C Cochet, M Le Borgne, M Engel, T Lomberget
– Journal of medicinal chemistry
(2019)
62,
1803
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.
B Bestgen, I Kufareva, W Seetoh, C Abell, RW Hartmann, R Abagyan, M Le Borgne, O Filhol, C Cochet, T Lomberget, M Engel
– J Med Chem
(2019)
62,
1817
Single-cell analysis identifies thymic maturation delay in growth-restricted neonatal mice
WA Bacon, RS Hamilton, Z Yu, J Kieckbusch, D Hawkes, AM Krzak, C Abell, F Colucci, DS Charnock-Jones
– Frontiers in immunology
(2018)
9,
2523
Unexpected stability of aqueous dispersions of raspberry-like colloids
Y Lan, A Caciagli, G Guidetti, Z Yu, J Liu, VE Johansen, M Kamp, C Abell, S Vignolini, OA Scherman, E Eiser
– Nat Commun
(2018)
9,
3614
Cucurbit[7]uril-based high-performance catalytic microreactors.
X Ren, Z Yu, Y Wu, J Liu, C Abell, OA Scherman
– Nanoscale
(2018)
10,
14835
Droplet-based microfluidic analysis and screening of single plant cells.
Z Yu, CR Boehm, JM Hibberd, C Abell, J Haseloff, SJ Burgess, I Reyna-Llorens
– PLoS One
(2018)
13,
e0196810
Patterned Arrays of Supramolecular Microcapsules
J Zhang, J Liu, Z Yu, S Chen, OA Scherman, C Abell
– Advanced Functional Materials
(2018)
28,
1800550
Fragment-Based Approach to Targeting Inosine-5 '-monophosphate Dehydrogenase (IMPDH) from &ITMycobacterium tuberculosis&IT
A Trapero, A Pacitto, V Singh, M Sabbah, AG Coyne, V Mizrahi, TL Blundell, DB Ascher, C Abell
– Journal of Medicinal Chemistry
(2018)
61,
2806
Supramolecular Nested Microbeads as Building Blocks for Macroscopic Self‐Healing Scaffolds
Z Yu, J Liu, CSY Tan, OA Scherman, C Abell
– Angewandte Chemie International Edition
(2018)
57,
3079
Supramolecular Nested Microbeads as Building Blocks for Macroscopic Self-Healing Scaffolds
Z Yu, J Liu, CSY Tan, OA Scherman, C Abell
– Angewandte Chemie
(2018)
130,
3133
Droplet microfluidics for the highly controlled synthesis of branched gold nanoparticles
S Abalde-Cela, P Taladriz-Blanco, MG de Oliveira, C Abell
– Scientific Reports
(2018)
8,
2440
Mass spectrometry for fragment screening
DS-H Chan, AJ Whitehouse, AG Coyne, C Abell
– Essays in Biochemistry
(2017)
61,
465
Target identification of $\textit{Mycobacterium tuberculosis phenotypic}$ hits using a concerted chemogenomic, biophysical and structural approach
G Mugumbate, V Mendes, M Blaszczyk, M Sabbah, G Papadatos, J Lelievre, L Ballell, D Barros, C Abell, TL Blundell, JP Overington
– Front Pharmacol
(2017)
8,
681