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  • Currently displaying 21 - 40 of 258 publications
Improved Photo Physical Properties of mEos3 for Single Molecule Tracking
L-M Needham, S Basu, E Taylor, ED Laue, D Klenerman, D Lando, SF Lee
– Biophysical Journal
(2016)
110,
485A
3D Super-Resolution Imaging of Unperturbed Cells
AR Carr, J McCol, AM Santos, J-E Lee, A Ponjavic, D Klenerman, S Davis, SF Lee
– Biophysical Journal
(2016)
110,
485A
Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis.
Y Zhang, J Clausmeyer, B Babakinejad, AL Córdoba, T Ali, A Shevchuk, Y Takahashi, P Novak, C Edwards, M Lab, S Gopal, C Chiappini, U Anand, L Magnani, RC Coombes, J Gorelik, T Matsue, W Schuhmann, D Klenerman, EV Sviderskaya, Y Korchev
– ACS Nano
(2016)
10,
3214
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids
MH Horrocks, SF Lee, S Gandhi, NK Magdalinou, SW Chen, MJ Devine, L Tosatto, M Kjaergaard, JS Beckwith, H Zetterberg, M Iljina, N Cremades, CM Dobson, NW Wood, D Klenerman
– ACS Chemical Neuroscience
(2016)
7,
399
PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits
MJ Broadhead, MH Horrocks, F Zhu, L Muresan, R Benavides-Piccione, J DeFelipe, D Fricker, MV Kopanitsa, RR Duncan, D Klenerman, NH Komiyama, SF Lee, SGN Grant
– Scientific reports
(2016)
6,
24626
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms.
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
– Scientific reports
(2016)
6,
28658
A single-molecule approach to deciphering the mechanism of T-cell receptor triggering.
KA Ganzinger, R Fernandes, S Lee, M Palayret, P Jonsson, J McColl, SJ Davis, D Klenerman
– MOLECULAR BIOLOGY OF THE CELL
(2016)
27,
Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.
E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, MH Horrocks, B Banushi, D Little, MJ Devine, P Gissen, D Klenerman, CM Dobson, NW Wood, S Gandhi, AY Abramov
– Antioxidants and Redox Signaling
(2016)
24,
376
Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States
SL Latty, JH Felce, L Weimann, SF Lee, SJ Davis, D Klenerman
– Biophys J
(2015)
109,
1798
The 2015 super-resolution microscopy roadmap
SW Hell, SJ Sahl, M Bates, X Zhuang, R Heintzmann, MJ Booth, J Bewersdorf, G Shtengel, H Hess, P Tinnefeld, A Honigmann, S Jakobs, I Testa, L Cognet, B Lounis, H Ewers, SJ Davis, C Eggeling, D Klenerman, KI Willig, G Vicidomini, M Castello, A Diaspro, T Cordes
– Journal of Physics D: Applied Physics
(2015)
48,
443001
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
– Anal Chem
(2015)
87,
8818
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
– Proceedings of the National Academy of Sciences of the United States of America
(2015)
112,
E1994
On-Demand Delivery of Single DNA Molecules Using Nanopipets
AP Ivanov, P Actis, P Jönsson, D Klenerman, Y Korchev, JB Edel
– ACS Nano
(2015)
9,
3587
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
– Journal of Neurochemistry
(2015)
133,
582
SICM-Based Nanodelivery System for Local TRPV1 Stimulation
A Lopez-Cordoba, P Joensson, B Babakinejad, P Actis, P Novak, T Yasufumi, A Shevchuck, U Anand, P Anand, A Drews, A Ferrer-Montiel, D Klenerman, Y Korchev
– BIOPHYSICAL JOURNAL
(2015)
108,
332A
Lipid peroxidation is essential for alpha-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
– J Neurochem
(2015)
133,
582
Single-molecule FRET reveals hidden complexity in a protein energy landscape.
M Tsytlonok, SM Ibrahim, PJE Rowling, W Xu, MJ Ruedas-Rama, A Orte, D Klenerman, LS Itzhaki
– Structure (London, England : 1993)
(2015)
23,
190
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, E Mandelkow, TPJ Knowles, E Mandelkow, D Klenerman
– Nature Communications
(2015)
6,
7025
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants.
L Tosatto, MH Horrocks, AJ Dear, TPJ Knowles, M Dalla Serra, N Cremades, CM Dobson, D Klenerman
– Scientific reports
(2015)
5,
16696
Aggregated α-synuclein and complex I deficiency: Exploration of their relationship in differentiated neurons
AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, D Klenerman, S Gandhi, DM Turnbull, AY Abramov
– Cell Death & Disease
(2015)
6,
e1820

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