Publications by Professor David Spring

Is synthesis the main hurdle for the generation of diversity in compound libraries for screening?

WRJD Galloway, DR Spring - Expert Opinion on Drug Discovery (2009) 4, 467
(DOI: 10.1517/17460440902916606)

Fluoride-free cross coupling using vinyldisiloxanes.

HF Sore, CM Boehner, SJF MacDonald, D Norton, DJ Foxd, DR Spring - Organic and Biomolecular Chemistry (2009) 7, 1068
(DOI: 10.1039/b900852g)

Towards quorum-quenching catalytic antibodies

PB Kapadnis, E Hall, M Ramstedt, WRJD Galloway, M Welch, DR Spring - Chemical Communications (2009), 538
(DOI: 10.1039/b819819e)

Synthesis of unprecedented scaffold diversity

WRJD Galloway, M Diaz-Gavilan, A Isidro-Llobet, DR Spring - Angew Chem Int Ed Engl (2009) 48, 1194
(DOI: 10.1002/anie.200805452)

Using chemical probes to investigate the sub-inhibitory effects of azithromycin

FG Glansdorp, RJ Spandl, JE Swatton, O Loiseleur, M Welch, DR Spring - Organic and Biomolecular Chemistry (2008) 6, 4120
(DOI: 10.1039/b813157k)

Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis

EE Wyatt, WRJD Galloway, GL Thomas, M Welch, O Loiseleur, AT Plowright, DR Spring - Chemical Communications (2008), 4962
(DOI: 10.1039/b812901k)

Synthesis of a biotin-labeled quorum-sensing molecule: Towards a general method for target identification

RJ Spandl, RL Nicholson, DM Marsden, JT Hodgkinson, XB Su, GL Thomas, GPC Salmond, M Welch, DR Spring - Synlett (2008) 2008, 2122
(DOI: 10.1055/s-2008-1077978)

Gemmacin B: Bringing diversity back into focus

A Robinson, GL Thomas, RJ Spandl, M Welch, DR Spring - Organic and Biomolecular Chemistry (2008) 6, 2978
(DOI: 10.1039/b809038f)

ORGN 157-Diversity oriented synthesis: From linear aminoalkenes to complex cyclic scaffolds

M Diaz-Gavilan, K O'Connell, F Benfatti, DR Spring - ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2008) 236

BIOL 47-Synthesis of a transition-state analog for the hydrolysis of N-acyl homoserine lactones

PB Kapadnis, E Hall, M Welch, DR Spring - ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2008) 236