Publications by Dr David Spring

Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space

E van der Horst, JE Peironcely, GJP van Westen, OO van den Hoven, WRJD Galloway, DR Spring, JK Wegner, HWT van Vlijmen, AP IJzerman, JP Overington, A Bender - Current Topics in Medicinal Chemistry (2011) 11, 1964

Chemical genetics

CJO Connor, L Laraia, DR Spring - Chemical Society Reviews (2011) 40, 4332
(DOI: 10.1039/c1cs15053g)

Robust routes for the synthesis of N-acylated-L-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity

JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, XB Su, GPC Salmond, M Welch, DR Spring - Tetrahedron Letters (2011) 52, 3291
(DOI: 10.1016/j.tetlet.2011.04.059)

Regioselectivity in Thermal Rhodium(II)-Catalysed Büchner-Type Reactions of Substituted Aryl Halides: Studies towards the Synthesis of Halide-Substituted Cycloheptatrienes

EE Wyatt, WRJD Galloway, DR Spring - Synlett (2011), 1449
(DOI: 10.1055/s-0030-1260562)

The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals.

S Poulter, TM Carlton, DR Spring, GPC Salmond - Mol Microbiol (2011) 80, 1120
(DOI: 10.1111/j.1365-2958.2011.07634.x)

Diversity-oriented synthesis of macrocyclic peptidomimetics

A Isidro-Llobet, T Murillo, P Bello, A Cilibrizzi, JT Hodgkinson, WRJD Galloway, A Bender, M Welch, DR Spring - Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 6793
(DOI: 10.1073/pnas.1015267108)

Controlling the contents of microdroplets by exploiting the permeability of PDMS

JU Shim, SN Patil, JT Hodgkinson, SD Bowden, DR Spring, M Welch, WTS Huck, F Hollfelder, C Abell - Lab on a Chip - Miniaturisation for Chemistry and Biology (2011) 11, 1132
(DOI: 10.1039/C0LC00615G)

Rational methods for the selection of diverse screening compounds

DJ Huggins, AR Venkitaraman, DR Spring - ACS Chem Biol (2011) 6, 208
(DOI: 10.1021/cb100420r)

Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls

JL Kenwright, WRJD Galloway, DT Blackwell, A Isidro-Llobet, J Hodgkinson, L Wortmann, SD Bowden, M Welch, DR Spring - Chemistry (2011) 17, 2981
(DOI: 10.1002/chem.201002093)

Drug discovery: A question of library design.

PJ Hajduk, WR Galloway, DR Spring - Nature (2011) 470, 42
(DOI: 10.1038/470042a)