Publications by Professor David Spring

Using ligand-mapping simulations to design a ligand selectively targeting a cryptic surface pocket of polo-like kinase 1

YS Tan, P Śledź, S Lang, CJ Stubbs, DR Spring, C Abell, RB Best - Angew Chem Int Ed Engl (2012) 51, 10078
(DOI: 10.1002/anie.201205676)

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria.

WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring - Trends in Microbiology (2012) 20, 449
(DOI: 10.1016/j.tim.2012.06.003)

Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa

JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, M Welch, DR Spring - Organic and Biomolecular Chemistry (2012) 10, 6032
(DOI: 10.1039/c2ob25198a)

Palladium-Catalysed Cross-Coupling of Vinyldisiloxanes with Benzylic and Allylic Halides and Sulfonates

EC Frye, CJ O'Connor, DG Twigg, B Elbert, L Laraia, DG Hulcoop, AR Venkitaraman, DR Spring - Chemistry (2012) 18, 8774
(DOI: 10.1002/chem.201200431)

Diversity-oriented synthesis: producing chemical tools for dissecting biology.

CJ O' Connor, HS Beckmann, DR Spring - Chemical Society reviews (2012) 41, 4444
(DOI: 10.1039/c2cs35023h)

The effect of humidity on the ozonolysis of unsaturated compounds in aerosol particles

JWL Lee, V Carrascón, PJ Gallimore, SJ Fuller, A Björkegren, DR Spring, FD Pope, M Kalberer - Physical Chemistry Chemical Physics (2012) 14, 8023
(DOI: 10.1039/c2cp24094g)

Two-directional synthesis as a tool for diversityoriented synthesis: Synthesis of alkaloid scaffolds

KMG O'Connell, M Díaz-Gavilán, WRJD Galloway, DR Spring - Beilstein J Org Chem (2012) 8, 850
(DOI: 10.3762/bjoc.8.95)

Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs.

JT Hodgkinson, WR Galloway, M Welch, DR Spring - Nature protocols (2012) 7, 1184
(DOI: 10.1038/nprot.2012.054)

Coumarin-derived transformable fluorescent sensor for Zn 2+

Z Xu, X Liu, J Pan, DR Spring - Chemical Communications (2012) 48, 4764
(DOI: 10.1039/c2cc30963g)

Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity

SJ Zheng, L Laraia, CJO Connor, D Sorrell, YS Tan, ZC Xu, AR Venkitaraman, WJ Wu, DR Spring - Organic and Biomolecular Chemistry (2012) 10, 2590
(DOI: 10.1039/c2ob25065a)