Publications by Dr David Spring

Dynamic combinatorial chemistry with novel dithiol building blocks: Towards new structurally diverse and adaptive screening collections

TM Postma, WRJD Galloway, FBL Cougnon, GD Pantoş, JE Stokes, DR Spring - Synlett (2013) 24, 765

Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics

B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, KMG O'Connell, N Bartolucci, MD Valle, M Welch, DR Spring - Organic and Biomolecular Chemistry (2012) 10, 8452
(DOI: 10.1039/c2ob26501j)

A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.

KMG O'Connell, HSG Beckmann, L Laraia, HT Horsley, A Bender, AR Venkitaraman, DR Spring - Organic and Biomolecular Chemistry (2012) 10, 7545
(DOI: 10.1039/c2ob26272j)

Using ligand-mapping simulations to design a ligand selectively targeting a cryptic surface pocket of polo-like kinase 1

YS Tan, P Śledź, S Lang, CJ Stubbs, DR Spring, C Abell, RB Best - Angew Chem Int Ed Engl (2012) 51, 10078
(DOI: 10.1002/anie.201205676)

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria.

WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring - Trends in Microbiology (2012) 20, 449
(DOI: 10.1016/j.tim.2012.06.003)

Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa

JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, M Welch, DR Spring - Organic and Biomolecular Chemistry (2012) 10, 6032
(DOI: 10.1039/c2ob25198a)

Palladium-Catalysed Cross-Coupling of Vinyldisiloxanes with Benzylic and Allylic Halides and Sulfonates

EC Frye, CJ O'Connor, DG Twigg, B Elbert, L Laraia, DG Hulcoop, AR Venkitaraman, DR Spring - Chemistry (2012) 18, 8774
(DOI: 10.1002/chem.201200431)

Diversity-oriented synthesis: producing chemical tools for dissecting biology.

CJ O' Connor, HS Beckmann, DR Spring - Chemical Society reviews (2012) 41, 4444
(DOI: 10.1039/c2cs35023h)

The effect of humidity on the ozonolysis of unsaturated compounds in aerosol particles

JWL Lee, V Carrascón, PJ Gallimore, SJ Fuller, A Björkegren, DR Spring, FD Pope, M Kalberer - Physical Chemistry Chemical Physics (2012) 14, 8023
(DOI: 10.1039/c2cp24094g)

Two-directional synthesis as a tool for diversityoriented synthesis: Synthesis of alkaloid scaffolds

KMG O'Connell, M Díaz-Gavilán, WRJD Galloway, DR Spring - Beilstein J Org Chem (2012) 8, 850
(DOI: 10.3762/bjoc.8.95)