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Professor Jason Chin FMedSci

Portrait of jc482

Publications

Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling.
WD Lambert, SL Scinto, O Dmitrenko, SJ Boyd, R Magboo, RA Mehl, JW Chin, JM Fox, S Wallace
– Org Biomol Chem
(2017)
15,
6640
Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis
JA Gramespacher, AJ Stevens, DP Nguyen, JW Chin, TW Muir
– Journal of the American Chemical Society
(2017)
139,
8074
Biosynthesis and genetic encoding of phosphothreonine through parallel setection and deep sequencing
MS Zhang, SF Brunner, N Huguenin-Dezot, AD Liang, WH Schmied, DT Rogerson, JW Chin
– Nature methods
(2017)
14,
729
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium( ii ) catalyst
TTL Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
– Chem. Sci.
(2017)
8,
3871
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.
L Perdios, AR Lowe, G Saladino, TD Bunney, N Thiyagarajan, Y Alexandrov, C Dunsby, PMW French, JW Chin, FL Gervasio, EW Tate, M Katan
– Scientific reports
(2017)
7,
39841
Defining synonymous codon compression schemes by genome recoding
K Wang, J Fredens, SF Brunner, SH Kim, T Chia, JW Chin
– Nature
(2016)
539,
59
Genetic code expansion in the mouse brain.
RJ Ernst, TP Krogager, ES Maywood, R Zanchi, V Beránek, TS Elliott, NP Barry, MH Hastings, JW Chin
– Nature Chemical Biology
(2016)
12,
776
Tagging and Enriching Proteins Enables Cell-Specific Proteomics
TS Elliott, A Bianco, FM Townsley, SD Fried, JW Chin
– Cell Chem Biol
(2016)
23,
805
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.
N Huguenin-Dezot, V De Cesare, J Peltier, A Knebel, YA Kristaryianto, DT Rogerson, Y Kulathu, M Trost, JW Chin
– Cell Rep
(2016)
16,
1180
Genetically encoded optical activation of DNA recombination in human cells
J Luo, E Arbely, J Zhang, C Chou, R Uprety, JW Chin, A Deiters
– Chemical communications (Cambridge, England)
(2016)
52,
8529
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Research Group

Research Interest Group

Email address

chin@mrc-lmb.cam.ac.uk