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Dr Farah El Turk

Publications

Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD Mutations.
I Dikiy, B Fauvet, A Jovičić, A-L Mahul-Mellier, C Desobry, F El-Turk, AD Gitler, HA Lashuel, D Eliezer
– ACS Chem Biol
(2016)
11,
2428
Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein.
F El-Turk, FN Newby, E De Genst, T Guilliams, T Sprules, A Mittermaier, CM Dobson, M Vendruscolo
– Biochemistry
(2016)
55,
3116
Elucidating the Structural Basis of alpha-Synuclein Fibrillation using Small Camelid Nanobodies
F El Turk, G Tomba, E De Genst, T Guillams, P Kukic, M Vendruscolo, C Dobson
– BIOPHYSICAL JOURNAL
(2014)
106,
257A
Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, M Vendruscolo, N Cremades, E Pardon, L Wyns, ME Welland, J Steyaert, J Christodoulou, CM Dobson, E De Genst
– Journal of molecular biology
(2013)
425,
2397
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, M Vendruscolo, N Cremades, E Pardon, L Wyns, ME Welland, J Steyaert, J Christodoulou, CM Dobson, E De Genst
– Journal of Molecular Biology
(2013)
425,
2397
Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
F El-Turk, B Fauvet, A Ashrafi, H Ouertatani-Sakouhi, M-K Cho, M Neri, M Cascella, U Rothlisberger, F Pojer, M Zweckstetter, H Lashuel
– PLoS One
(2012)
7,
e45024
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action
H Ouertatani-Sakouhi, F El-Turk, B Fauvet, M-K Cho, D Pinar Karpinar, D Le Roy, M Dewor, T Roger, J Bernhagen, T Calandra, M Zweckstetter, HA Lashuel
– J Biol Chem
(2010)
285,
26581
An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity.
F El Turk, B Fauvet, H Ouertatani-Sakouhi, A Lugari, S Betzi, P Roche, X Morelli, HA Lashuel
– Bioorganic & medicinal chemistry
(2010)
18,
5425
Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.
H Ouertatani-Sakouhi, M Liu, F El-Turk, GD Cuny, MA Glicksman, HA Lashuel
– Journal of Biomolecular Screening
(2010)
15,
347
A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.
H Ouertatani-Sakouhi, F El-Turk, B Fauvet, T Roger, D Le Roy, DP Karpinar, L Leng, R Bucala, M Zweckstetter, T Calandra, HA Lashuel
– Biochemistry
(2009)
48,
9858
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Research Group

Telephone number

01223 336366 (shared)

Email address

fe237@cam.ac.uk