We are a group based in the Chemistry Department and also the Cambridge Research Institute (CRI) at the University of Cambridge. Research in our group is largely hypothesis driven and employs the principles of chemistry and the molecular sciences to address questions of importance in biology and molecular medicine.
The CRI based laboratory is the focus for experiements involving cell biology genomics and medicine which is complemented by the group's work and will complement the group's chemistry and molecular biophysics expertise in the Department of Chemistry The combination of both laboratories will enable us to undertake integrated research programmes that involve chemistry, biophysics, cell biology and molecular medicine.
Find out more about how the research group is working to unlock the mysteries of four-stranded DNA structures in The Gene Genie podcast.
A new publication from the Balasubramanian group demonstrates the quantitative visualisation of G-quadruplexes in human cells. The development of an engineered, structure-specific antibody has allowed us to study G-quadruplex formation during cell cycle progression, providing substantive evidence for the formation of these structures in mammalian cells. For more information, visit our Publications page.
New Wellcome Trust Award
We are pleased to have been awarded a Wellcome Trust Senior Investigator Award to study the chemical biology of the genome and epigenome. To learn more about our funding, visit our Sponsors and Funding page.