400 MHz QNP Spectrometer - 'Laphroaig' - Room B18
The 400 MHz spectrometer in B18 is one of our open access walk-up instruments. Formerly owned by Glaxo Smith Kline, this spectrometer is one of our busiest - running thousands of samples each year. It has a QNP probe which can observe 1H, and switchable 13C, 19F and 31P on the other channel - the switching is automatically carried out using a pneumatic system. The spectrometer is controlled by a bespoke GSK program, and submission of samples takes place on the separate computer. The experiments that this spectrometer will run are:
Proton 1H-no-print-only-pdf - Standard proton experiment - no printout - PDF only - Daytime
Proton 1H - Standard Proton experiment - Daytime
19F only - Standard Fluorine experiment - Daytime
Interpretation Aid - Standard Proton and Quick COSY experiments - Daytime
Quick 13C - Standard Proton and Quick 13C experiments - Daytime
Problem Solving - Proton, COSY, 13C, DEPT, HMQC experiments - Overnight
Advanced Problem Solving - Proton, COSY, HMQC, HMBC experiments - Overnight
Sensitive 1H - 256 scan Proton experiment - Overnight
Fluorine - Proton, 19F, and 19F Proton decoupled experiments - Overnight
Phosphorus - Proton, 31P and 31P Proton decoupled experiments - Overnight
Proton 1H and 13C - Proton, 13C and DEPT experiments - Overnight
All data will be emailed to you if you type your email address into the comments box, regardless of experiment chosen.
The experiments are queued in order of submission for daytime and overnight experiments and the machine automatically works through the list in turn. Daytime experiments will run overnight if there is spare time. The overnight period runs from 7pm to 8am. Users may wish to consider running their samples on the other open-access spectrometer (Lagavulin) once the overnight period commences, as it is set up to allow daytime experiments until midnight.
When submitting samples to the instrument would all users please stick to the following convention:
Group Code followed by /, then your personal identifying code. For example MJG/ABC32_10_Fr2 or JKMS/RJM-11-1a
By following these rules it makes things much easier when preparing the usage lists at the end of each month.
You can view the samples waiting and the samples done by accessing the auto-updating web pages through the backup server Scapa.
Navigate to \\scapa\NMRshares\laphroaig-queue
Every hour the system sorts zipped data into a folder on the backup server according to your group code. This can be found at \\scapa.ch.cam.ac.uk\NMRarchives\zips
Please remember to collect your tubes promptly after they have been run. Tubes left in the room are cleared every Tuesday morning around 9am and can be found in the labelled beaker in the fume hood in B28.
